@article{Yao2026, 
author = {Lan Yao and Shiyu Li and Jinxiu Zhang and Zhuang Li and Jianhua Lv},
title = {Ten previously undescribed norsesquiterpenoids from the fungus Marasmiellus candidus and their anti-inflammatory activities},
year = {2026},
journal = {Mycology},
volume = {17},
number = {2},
pages = {531-542},
keywords = {Marasmiellus candidus, secondary metabolite, sesquiterpenoids, anti-inflammatory activity},
url = {https://www.sciopen.com/article/10.1080/21501203.2025.2551650},
doi = {10.1080/21501203.2025.2551650},
abstract = {In this study, ten undescribed norsesquiterpenoids, named marasmiellactones R−U (1−4) and marasmielolic acids A−F (5−10), were isolated from the cultures of the fungus Marasmiellus candidus. Their planar structures were characterised using comprehensive spectroscopic techniques, including 1D/2D NMR and HRESIMS, while the absolute configurations were determined by comparing experimental and calculated ECD spectra. In addition, the anti-inflammatory activities of isolated compounds were evaluated by using an LPS-induce RAW 264.7 cell model. Compounds 1−4 demonstrated good anti-inflammatory activity, with IC50 values of 18.2, 16.7, 22.1, and 15.5 μmol/L, respectively.}
}