@article{Esmaili-Badrabadi2026, 
author = {Parvin Esmaili-Badrabadi and Payam Nabovati and Morad Amir Ahmad and Abdollah Farzaneh and Asgar Doostdar and Abbasali Yekta and Mahdi Mahmoodi and Mohammad Saeid Hoseinzade and Mehdi Khabazkhoob},
title = {Impact of a three-month period of mini-scleral lens usage on intraocular pressure and the anterior chamber angle in patients with keratoconus},
year = {2026},
journal = {International Journal of Ophthalmology},
volume = {19},
number = {8},
pages = {1510-1517},
keywords = {keratoconus, mini-scleral lens, intraocular pressure, anterior chamber angle},
url = {https://www.sciopen.com/article/10.18240/ijo.2026.08.08},
doi = {10.18240/ijo.2026.08.08},
abstract = {AIMTo investigate the long-term effects of mini-scleral lens wear on intraocular pressure (IOP) and anterior chamber angle (ACA) in patients with keratoconus (KCN).METHODSA convenience sampling method was adopted to enroll KCN patients between November 2023 and April 2024. All participants had a definitive KCN diagnosis and were eligible for mini-scleral lens fitting. Baseline optometric examinations included visual acuity measurement, objective and subjective refraction, and slit-lamp biomicroscopy. Mini-scleral lenses were fitted with trial lenses. Participants returned for a 3-month follow-up, where all examinations were repeated.RESULTSSeventeen KCN patients (12 males) were enrolled, aged 20–53y with a mean age of 38.09±12.86y. Mean IOP rose by 0.33±1.60 mm Hg after mini-scleral lens wear, without statistical significance (P=0.525). The nasal ACA increased by 0.73°±2.69° (P=0.390), whereas the temporal ACA decreased by −1.46°±3.10° (P=0.152). In severe KCN cases, mean IOP elevated from 7.60±0.96 to 8.60±1.14 mm Hg after lens fitting. By contrast, mild-to-moderate KCN patients showed a slight IOP decline from 11.58±2.50 mm Hg at baseline to 11.33±2.42 mm Hg post-fitting. Females presented a statistically significant reduction in temporal ACA after lens wear (P=0.020). Older baseline age was negatively correlated with temporal ACA width (β=−0.719, P=0.041).CONCLUSIONPatients with advanced KCN face higher risks of IOP elevation after mini-scleral lens fitting. ACA changes induced by mini-scleral lenses vary by sector, with temporal angle narrowing being more prominent. Clinicians should closely monitor potential temporal angle narrowing, especially in female and older KCN patients during mini-scleral lens fitting.}
}