@article{Ji2026, 
author = {Quanbao Ji and Ruhu Lao},
title = {Effect of the striatum on    β-synchronous oscillatory activity},
year = {2026},
journal = {Electronic Research Archive},
volume = {34},
number = {4},
pages = {2402-2418},
keywords = {Parkinson's disease, β-band synchrony, striatum, phase-locking value, phase consistency},
url = {https://www.sciopen.com/article/10.3934/era.2026110},
doi = {10.3934/era.2026110},
abstract = {Parkinson's disease (PD) is characterized by increased    β-band (13–30 Hz) synchronization. Although previous studies have indicated that the striatum plays a crucial part in generating and transmitting the    β-band oscillations, the underlying biophysical basis remains unclear. An extended thalamic–basal ganglia (BGTC) model including the striatum (BGSTC) is used to examine the striatal influence on    β-band synchronous oscillations in the globus pallidus pars interna (GPi). This influence is implemented by modulating striatal inhibitory input. Phase-locking value (PLV) and phase consistency (PC) show that the basal ganglia (BG) network exhibits pronounced    β-band synchrony in the Parkinsonian state. Moreover, enhancing striatal synaptic inputs may induce    β-band desynchronization in GPi via the direct pathway. In contrast, the modulation via the indirect pathway has a much weaker influence and may even exert an opposite effect. These conclusions not only reveal the striatum's regulatory capacity, but also provide a new avenue for PD therapy.}
}