@article{LI2005, 
author = {Zhidong LI and Weiwei WANG and Fangfang ZHOU and Xia GAO and Gaonong PENG and Huaxi XU and Ye-Guang CHEN},
title = {Interaction of Stathmin-Like 2 Protein with the APP Intracellular Domain},
year = {2005},
journal = {Tsinghua Science and Technology},
volume = {10},
number = {4},
pages = {484-488},
keywords = {Alzheimer's disease (AD), yeast two-hybrid, stathmin, amyloid precursor protein (APP), stathmin-like 2 protein (STMN2)},
url = {https://www.sciopen.com/article/10.1016/S1007-0214(05)70104-8},
doi = {10.1016/S1007-0214(05)70104-8},
abstract = {Amyloid precursor protein (APP) plays a critical role in the formation of Alzheimer’s disease (AD). The intracellular domain APP (AID) was suggested to cause neurotoxicity in the nucleus. To investigate the functions AID, yeast two-hybrid screening was performed to identify the proteins which interact with AID. The human brain cDNA library was screened using pGBKT7-AID as a bait, and several positive clones were identified. One of them encodes a part of the human stathmin-like 2 protein (STMN2). The interaction between STMN2 and APP implies that STMN2 may have an important function in APP-mediated AD formation.}
}