TY - JOUR AU - WANG, Yuhang AU - DI, Bin AU - YANG, Yong AU - JIANG, Cheng PY - 2026 TI - Progress of innovative drug research in China JO - Journal of China Pharmaceutical University SN - 1000-5048 SP - 275 EP - 287 VL - 57 IS - 3 AB - In recent years, China’s capacity for new drug research and development has been significantly strengthened, with major breakthroughs across multiple therapeutic areas, including cancer, autoimmune diseases, and metabolic disorders. An increasing number of domestically developed innovative drugs have been approved for marketing, gradually establishing a competitive position against imported drugs and expanding into global markets. This article systematically reviews the latest research progress of Class 1 innovative drugs in China from 2023 to 2024, categorizes representative approved drugs by therapeutic area, summarizes the clinical advantages and characteristics of representative drugs approved, analyzes in depth the current development trends of and challenges for China’s innovative pharmaceutical industry, and explores future directions, aiming to provide some reference for innovative drug research, industrial development, and policy-making in China. UR - https://doi.org/10.11665/j.issn.1000-5048.2026042802 DO - 10.11665/j.issn.1000-5048.2026042802