TY - JOUR AU - Xiang, Yanyu AU - Wang, Aiping PY - 2023 TI - On symmetry of the product of two higher-order quasi-differential operators JO - AIMS Mathematics SP - 9483 EP - 9505 VL - 8 IS - 4 AB - The symmetric realizations of the product of two higher-order quasi-differential expressions in Hilbert space are investigated. By means of the construction theory of symmetric operators, we characterize symmetric domains determined by two-point boundary conditions for product of two symmetric differential expressions with regular or limit-circle singular endpoints. The presented result contains the characterization of self-adjoint domains as a special case. Several examples of singular symmetric product operators are given. UR - https://doi.org/10.3934/math.2023478 DO - 10.3934/math.2023478