@article{SHEN2006, 
author = {Shufeng SHEN and Zhidong CHANG and Xinghua SUN and Xin HU and Huizhou LIU},
title = {Application of Block Copolymer in Three-Liquid-Phase Extraction System},
year = {2006},
journal = {Tsinghua Science and Technology},
volume = {11},
number = {2},
pages = {248-251},
keywords = {three-liquid-phase extraction system, block copolymer, phenoxymethyl penicillin, recovery},
url = {https://www.sciopen.com/article/10.1016/S1007-0214(06)70184-5},
doi = {10.1016/S1007-0214(06)70184-5},
abstract = {A novel three-liquid-phase extraction system (TES) composed of butyl acetate, block copolymer polyethylene oxide-polypropylene oxide-polyethylene oxide and ammonium sulphate aqueous solution [(NH4)2SO4] as top, middle, and bottom phase, respectively, has been developed. The copolymer recycling and partitioning behavior of penicillin V has been studied in this system. Results show that the copolymer could be purified and recycled and penicillin V of the filtrated ferment broth could be partitioned unevenly among the phases and purified in the top phase of this TES. About 90 wt.% of penicillin V could be distributed into the top phase around pH 2.5 and only less than 0.1 wt.% left in the bottom phase.}
}