@article{Mu2026, 
author = {Qing-Qing Mu and Ping Ge and Xu Liu and Jun Jia and Na Cui and Xiang-Xiang Yang and Rui-Xue Zhang and Yan Liu and Yuan-Yuan Zhang and Yuan He},
title = {Differences of the lamina cribrosa between primary open angle glaucoma and non-pathologic high myopia},
year = {2026},
journal = {International Journal of Ophthalmology},
volume = {19},
number = {6},
pages = {1177-1185},
keywords = {non-pathologic high myopia, primary open angle glaucoma, optic disc, lamina cribrosa, retinal nerve fiber layer},
url = {https://www.sciopen.com/article/10.18240/ijo.2026.06.19},
doi = {10.18240/ijo.2026.06.19},
abstract = {Primary open angle glaucoma (POAG) is a chronic, blinding ocular disorder characterized by progressive degeneration of retinal ganglion cells (RGCs). Its incidence and prevalence of blindness continue to increase with global population aging. Non-pathologic high myopia (HM) has been established as an independent risk factor for POAG, and the two conditions share similar structural changes in the lamina cribrosa (LC) during the early phase of optic nerve injury. This review summarizes the common and distinct pathological alterations of LC in POAG and HM, with the aim of clarifying its central role in the initiation and progression of optic nerve damage. Elucidating these similarities and differences may facilitate early detection and targeted intervention strategies for at-risk individuals from a structural perspective.}
}