@article{Guan2026, 
author = {Fangnian Guan and Jiayi Xu and Binbin Lei and Zhenghong Huang and Lulin Liu and Hao Li and Yanlin Liu and Zhien Pu and Wei Li and Qiantao Jiang and Houyang Kang and Jian Ma and Pengfei Qi and Qiang Xu and Yazhou Zhang and Mei Deng and Fengtao Wang and Yuming Wei and Yunfeng Jiang and Guoyue Chen},
title = {Identification of YrBK, an all-stage stripe rust resistance gene in a recombination-suppressed pericentromeric region of chromosome 1B in a Chinese wheat landrace},
year = {2026},
journal = {The Crop Journal},
volume = {14},
number = {2},
pages = {495-504},
keywords = {Genetic resources, Marker-assisted selection, Puccinia striiformis, Wheat},
url = {https://www.sciopen.com/article/10.1016/j.cj.2025.10.008},
doi = {10.1016/j.cj.2025.10.008},
abstract = {Stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a major disease constraining global wheat production. The Chinese wheat landrace Baikeheshangmai (BK) exhibits high-level, all-stage resistance (ASR) to this disease. The genetic basis of this resistance was investigated by analyzing a recombinant inbred line (RIL) population derived from cross BK × Avocet S using bulked-segregant exome capture sequencing (BSE-seq). Two resistance genes were identified: a major ASR gene, provisionally designated YrBK, and the adult-plant resistance (APR) gene Yr18. Across multiple environments, YrBK and Yr18 explained 12.47%–30.32% and 9.74%–20.56% of the phenotypic variance, respectively, and the two genes displayed a significant additive effect. Genetic mapping using a population of 4474 individuals, derived from the residual heterozygous lines, narrowed YrBK to a 0.181 cM genetic interval on chromosome arm 1BL. This genetic interval corresponds to a 56.16 Mb physical region characterized by suppressed recombination, precluding further map-based cloning. Within this interval, integrative candidate analysis combining expression profiles and SNP variation did not reveal a clear candidate from canonical resistance gene families, such as NLRs or kinases. Nevertheless, robust KASP markers co-segregating with YrBK were validated across diverse germplasm, enabling efficient marker-assisted selection. This study reports an effective genetic resource (YrBK) and provides molecular tools for marker-assisted selection. This gene will contribute to diversification of stripe rust resistance in wheat breeding.}
}