@article{He2025, 
author = {Junzhou He and Miao Yu and Saichong Zhang and Qianshun Liang and Mingrui Cao and Hongtao Xu and Xin Li and Zhenhai Sun and Zhijian Liu},
title = {Quantitative evaluation of H2O2 disinfection efficiency in air duct: Effects of temperature, relative humidity and H2O2 concentration},
year = {2025},
journal = {Building Simulation},
volume = {18},
number = {12},
pages = {3261-3274},
keywords = {hydrogen peroxide, bioaerosol, air disinfection, parametric assessment, sensitive constant},
url = {https://www.sciopen.com/article/10.1007/s12273-025-1381-0},
doi = {10.1007/s12273-025-1381-0},
abstract = {Hydrogen peroxide (H2O2) is widely used for disinfection because of its oxidative and antimicrobial properties. However, most studies have focused on surface disinfection, with limited research addressing its effectiveness for air disinfection. In this study, we developed a controlled air duct testing system to evaluate the disinfection performance of H2O2 in a ventilation system while precisely regulating environmental parameters. A sensitivity constant (Z) was introduced to quantitatively assess disinfection efficiency, with increased Z-values indicating enhanced disinfection performance. With a 7.5 s flow in the air duct system, the bioaerosol removal efficiency ranged from 26% to 97% under different temperature and humidity conditions. As temperature increased from 15 to 33 ℃, removal efficiency of Serratia marcescens and Escherichia coli increased from 40% to 95% and 78% to 97%, respectively. Correspondingly, Z-values increased from 0.0021 to 0.0076 ppm−1s−1 for S. marcescens and from 0.0072 to 0.0083 ppm−1s−1 for E. coli, suggesting that elevated temperature enhanced H2O2’s air disinfection efficiency. Conversely, higher humidities reduced H2O2’s efficacy; as the relative humidity decreased from 80% to 30%, the relative concentration of E. coli decreased and the Z-value dropped from 0.017 to 0.0022 ppm−1s−1. When the H2O2 concentration increased, the removal efficiency increased slightly, while the Z-value decreased significantly, indicating diminishing returns at higher H2O2 concentrations. These findings provide important insights for optimizing H2O2-based air disinfection strategies.}
}