@article{Liu2026, 
author = {Ziyang Liu and Xiang Yang and Xulin Zhou and Yiping Ning and Bingqing Wang and Aijuan Han and Yanjun Lin and Junfeng Liu and Xue Duan},
title = {Defect-rich Mg(OH)2 nanosheets as high-performance antioxidants},
year = {2026},
journal = {Nano Research},
volume = {19},
number = {4},
pages = {94908409},
keywords = {antioxidant, free radical, scavenger, Mg(OH)2, oxygen defect},
url = {https://www.sciopen.com/article/10.26599/NR.2026.94908409},
doi = {10.26599/NR.2026.94908409},
abstract = {The development of highly efficient radical scavengers remains a substantial challenge in materials chemistry. Here, we report defect-rich Mg(OH)2 nanosheets (d-Mg(OH)2), synthesized via rapid nucleation within a colloid mill, as a potent multifunctional antioxidant. Compared to commercial Mg(OH)2 (c-Mg(OH)2), d-Mg(OH)2 demonstrates markedly superior scavenging capabilities against a broad spectrum of radicals, including ·O2−, ·OH, ·NO, DPPH·, and ·Cl. Mechanistic investigations and density functional theory calculations reveal a dual-mode scavenging mechanism: hydrogen atom transfer for ·OH, ·NO, and ·Cl, and electron transfer for ·O2− and DPPH·, with significantly reduced energy barriers on the defect-rich surface. We further demonstrate the material’s practical efficacy in scavenging intracellular reactive oxygen species and enhancing the thermal stability of polyvinyl chloride. This work establishes a defect-engineering approach to activate earth-abundant hydroxides as high-performance antioxidants, with promising applications in biomedicine and polymer stabilization.}
}