@article{Feng2025, 
author = {Shubin Feng and Juan Du and Xinru Xie and Yiru Li and Chuyuan Yu and Liling Cui and Mingcan Xue and Chenxi Zhang},
title = {A bibliometric analysis of mechanisms and linkage studies on neurological disorders and statins over the past 20 years},
year = {2025},
journal = {Precision  Medication},
volume = {2},
number = {3},
keywords = {Neurological disorders, Statins, Bibliometric studies, Alzheimer's disease, Multiple sclerosis, Cholesterol, Atorvastatin},
url = {https://www.sciopen.com/article/10.1016/j.prmedi.2025.100049},
doi = {10.1016/j.prmedi.2025.100049},
abstract = {BackgroundNeurological disorders are one of the major contributors to the burden of disease, affecting the quality of life of the global population.Statins, known for their cholesterol-lowering properties, have garnered substantial interest due to their potential neuroprotective effects and association with subjective cognitive decline.The study aims to provide a comprehensive bibliometric analysis of the literature on the nexus between neurological disorders and statins.MethodsUsing VOSviewer (1.6.20), CiteSpace (6.3.1 and 5.7.R2), and R (4.4.1), the systematic bibliometric analysis offers valuable insights into the research landscape of neurological disorders and statins from 2004 to 2024.ResultsThe findings reveal a notable increase in scholarly output on neurological disorders and statins over the past two decades, with a particular emphasis on clinical trials and pharmacological mechanisms of statins. The remarkable multidisciplinary nature of the field is an important reason for its continued development.Compared to initial exploratory research, recent studies have placed increased emphasis on the neuroprotective roles of statins and their therapeutic potential in managing neurological disorders.Future research is anticipated to focus on precision medicine and personalized therapeutic strategies involving statins.The United States, China and Germany are leading the way in this field of research.ConclusionThe study's findings are instrumental in informing future research directions and contribute to a broader understanding of the subject matter across various scientific disciplines. Statins have great potential in the treatment of neurological disorders and neuroprotection and are moving towards customized medicine and personalized therapy.}
}