@article{XIONG2025, 
author = {Yaqing XIONG and Xizhen SUN and Xingting NI and Xin WU and Ling YAN and Yang LIU and Zhian HUANG and Jiaosheng ZHU and Jinxia MENG and Weifang SHI and Qiang LI and Qiang YANG},
title = {Physiologically active substances in herbal Baijiu based on multi-technology combination},
year = {2025},
journal = {China Brewing},
volume = {44},
number = {8},
pages = {212-220},
keywords = {multi-technology combination, herbal Baijiu, physiologically active substance},
url = {https://www.sciopen.com/article/10.11882/j.issn.0254-5071.2025.08.031},
doi = {10.11882/j.issn.0254-5071.2025.08.031},
abstract = {In this experiment, using herbal Baijiu as the research object, the physiologically active substances in herbal Baijiu were qualitatively and quantitatively analyzed by a combination of full two-dimensional gas chromatography-high-throughput time-of-flight mass spectrometry (GC×GC-TOFMS), ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-TOF-MS), inductively coupled plasma mass spectrometry (ICP-MS), high performance liquid chromatography (HPLC), ion chromatography (IC), gas chromatography-mass spectrometry (GC-MS), and amino acid analyzer (AAA). The results showed that 1179 volatiles substances, 427 non-volatiles substances, and 10 mineral elements were identified, respectively, and p-menthane-1,3,8-triene, carotene, (+)-longifolium, and other terpenoids were detected for the first time in herbal Baijiu. With the literature search, a total of 109 physiologically active substances were identified in 10 categories including 16 flavonoids, 1 polysaccharide, 1 alkaloid, 11 amino acids, 10 mineral elements, 8 organic acids and esters, 8 polyols, 14 pyrazines, 35 terpenes and their derivatives, and 5 phenols. The total contents of physiologically active substances in herbal Baijiu was 3.7-7.0 g/L, with the highest content of organic acid esters (3.4-6.8 g/L), and followed by amino acids (95.6-129.8 mg/L), flavonoids (104.2-138.7 mg/L), and polyols (11.6-26.0 mg/L), which had the effect of reducing liver damage, assisting in lowering blood lipids, and immunomodulation.}
}