@article{Li2025, 
author = {Haofan Li and Qiu Peng and Linda Oyang and Wenjuan Yang and Shizhen Li and Yaqian Han and Mingjing Peng and Shiming Tan and Longzheng Xia and Jinguan Lin and Xuemeng Xu and Nayiyuan Wu and Yanyan Tang and Xia Luo and Xianjie Jiang and Qianjin Liao and Yujuan Zhou},
title = {The regulatory role and mechanism of energy metabolism and immune response in head and neck cancer},
year = {2025},
journal = {Genes & Diseases},
volume = {12},
number = {6},
pages = {101607},
keywords = {Amino acid metabolism, Glucose metabolism, Head and neck cancer, Immune response, Lipid metabolism, Therapy},
url = {https://www.sciopen.com/article/10.1016/j.gendis.2025.101607},
doi = {10.1016/j.gendis.2025.101607},
abstract = {Head and neck cancer, which includes cancers of the mouth, larynx, and pharynx, is one of the six most common cancers worldwide. Common risk factors include smoking, excessive alcohol consumption, betel nut chewing, and viruses such as HPV and EBV. Tumor cells often exhibit distinct metabolic characteristics compared with normal cells, highlighting a key area for potential intervention. By targeting these metabolic pathways, it is possible to influence tumor initiation and progression. Therefore, this review primarily describes the alterations in glucose metabolism, amino acid metabolism, lipid metabolism, and the immune system in head and neck cancer patients and discusses potential treatment strategies to advance the understanding of head and neck cancer and the development of therapeutic drugs for it.}
}