TY  - JOUR
AU  - LIANG, Shuo
AU  - GAO, Lianyin
AU  - LIN, Fangbing
AU  - BAI, Chen
AU  - GENG, Yuzhen
AU  - CHE, Niancong
PY  - 2025
TI  - Theoretical reconstruction study of the pathogenesis of jaundice under the theory of "intermingling of dampness and blood stasis and integration of liver and spleen"
JO  - Journal of Beijing University of Traditional Chinese Medicine
SN  - 1006-2157
SP  - 1234
EP  - 1241
VL  - 48
IS  - 9
AB  - In traditional Chinese medicine, jaundice is a liver and gallbladder disorder, primarily characterized by yellowing of the eyes, skin, and urine, with ocular yellowing being the most prominent feature. The understanding of jaundice pathogenesis in traditional Chinese medicine can be traced back to the Inner Canon of Huangdi. Despite the continuous development and improvement of successive generations of medical practitioners and a rich theoretical understanding of its pathogenesis being formed by the end of the Qing Dynasty, no unified view exists on whether the core pathological factor was dampness or blood stasis, nor on whether the primary disease location lay in the spleen and stomach or the liver and gallbladder. This article re-examines historical perspectives on jaundice pathogenesis within the context of traditional Chinese medicine theory, focusing on two key issues: pathological factors and the location of Zang and Fu. By integrating modern research approaches based on compound pathogenesis theory, and considering pathological factors, disease location according to Zang and Fu, and disease progression, a theoretical model is reconstructed, centered on the intermingling of dampness and blood stasis and integration of liver and spleen. Additionally, the insights and therapeutic strategies of multiple renowned clinical hepatology experts are incorporated to enrich the theoretical framework for jaundice treatment in traditional Chinese medicine and to enhance clinical efficacy.
UR  - https://doi.org/10.3969/j.issn.1006-2157.2025.09.008
DO  - 10.3969/j.issn.1006-2157.2025.09.008