TY  - JOUR
AU  - Xie, Juan
AU  - Zhang, Tingting
AU  - Jiang, Jirui
AU  - Xue, Wen
AU  - Wang, Wenhui
AU  - Ni, Jiahua
AU  - Zhang, Xiaonong
AU  - Liu, Xuanyong
PY  - 2025
TI  - Advances in magnesium-based implants for biomedical applications: A comprehensive review and future perspectives
JO  - Journal of Magnesium and Alloys
SN  - 2213-9567
SP  - 2978
EP  - 3003
VL  - 13
IS  - 7
AB  - Biodegradable magnesium (Mg)-based metals can undergo spontaneous corrosion and full degradation in the human body, releasing magnesium ions, hydroxides, and hydrogen. Mg and its alloys have shown preliminary success as an implantable biomaterial. Current research on biodegradable Mg-based metals addresses clinical challenges, including material design and preparation, property enhancement, and exploring relevant biological functions. This review provides a comprehensive overview of the biomedical applications of Mg-based implants across eight fields: cardiovascular, orthopedics, stomatology, general surgery, neurosurgery, fat metabolism, and other potential areas, building upon previously published work. The challenges and prospects of biodegradable Mg-based implants in these application fields are discussed.
UR  - https://doi.org/10.1016/j.jma.2025.05.009
DO  - 10.1016/j.jma.2025.05.009