@article{ZHANG2025, 
author = {Shuai ZHANG and Yu WANG and Pengfei XIE and Huijia LIU and Lijun CHEN and Yichao HUANG and Kaiyong LIU and Dianbing ZHOU and Yuxin LIU and Xu LIU and Wei SONG},
title = {Determination of 11 Phthalate Monoesters in Crucian Carp by QuEChERS Coupled with Ultra-high Performance Liquid Chromatography-Tandem Mass Spectrometry},
year = {2025},
journal = {Food Science},
volume = {46},
number = {19},
pages = {281-289},
keywords = {phthalate monoesters, crucian carp, ultra-high performance liquid chromatography-tandem mass spectrometry, quick, easy, cheap, effective, rugged, safe},
url = {https://www.sciopen.com/article/10.7506/spkx1002-6630-20250415-118},
doi = {10.7506/spkx1002-6630-20250415-118},
abstract = {A rapid sample preparation system based on the quick, easy, cheap, effective, rugged, safe (QuEChERS) method was developed for the multi-residue detection of phthalate monoesters (mono-PAEs) in crucian carp by ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The samples (1.00 g) underwent extraction with 98% acetonitrile in formic acid, purified using the QuEChERS method, blown down to near dryness under nitrogen gas, reconstituted in acetonitrile:water (1:1, V/V) solution, and filtered through a membrane filter before injection for analysis. The calibration curves for 11 mono-PAEs exhibited good linearity (R2 ≥ 0.99903). The limits of detection and quantification were 3.00 and 10.00 μg/kg, respectively. At four spiked concentration levels of 10, 20, 100 and 200 μg/kg, the recoveries of these mono-PAEs ranged from 68.12% to 109.93%, 74.43% to 112.46%, 84.92% to 109.48%, and 82.18% to 108.92%, respectively, with relative standard deviation (RSD) of 1.06% to 8.50%, 0.82% to 4.07%, 0.63% to 2.14%, and 0.79% to 2.66%, respectively. The method exhibited good reproducibility, its recoveries meeting the testing requirements, was simple to operate and sensitive. Therefore, it could meet the need for the trace analysis of multiple mono-PAEs in crucian carp matrices.}
}