TY  - JOUR
AU  - Liu, Chang
AU  - Tian, Lei
AU  - Yu, Wenbo
AU  - Wang, Yu
AU  - Yao, Ziqing
AU  - Liu, Yue
AU  - Yang, Luomiao
AU  - Liu, Chunjuan
AU  - Shi, Xiaolong
AU  - Liu, Tao
AU  - Chen, Bingru
AU  - Wang, Zhenguo
AU  - Yu, Haiqiu
AU  - Zhou, Yufei
PY  - 2025
TI  - Natural variation in SbTEF1 contributes to salt tolerance in sorghum seedlings
JO  - Journal of Integrative Agriculture (JIA)
SN  - 2095-3119
SP  - 4168
EP  - 4181
VL  - 24
IS  - 11
AB  - Salt stress is a major constraint to crop productivity and quality. The limited availability of salt-tolerant genes poses significant challenges to breeding programs aimed at enhancing salt tolerance. Sorghum displays a remarkable ability to withstand saline conditions; therefore, elucidating the genetic underpinnings of this trait is crucial. This study entailed a comprehensive resequencing of 186 sorghum accessions to perform a genome-wide association study (GWAS) focusing on relative root length (RL) and root fresh weight (RFW) under salt stress conditions. We identified eight candidate genes within a co-localized region, among which SbTEF1 - a gene encoding a transcription elongation factor protein - was deemed a potential candidate due to its annotation and expression pattern alterations under salt stress. Haplotype analysis, gene cloning, linkage disequilibrium (LD) analysis, and allele effect analysis revealed that PAV284, located in the promoter region of SbTEF1, modulated gene expression under salt stress, which, in turn, influenced sorghum seedlings’ salt tolerance. PAV284 holds promise as a genetic marker for selecting salt-tolerant germplasm via marker-assisted breeding, enhancing the development of salt-tolerant sorghum cultivars.
UR  - https://doi.org/10.1016/j.jia.2024.03.030
DO  - 10.1016/j.jia.2024.03.030