@article{ZHOU2022, 
author = {Lijing ZHOU and Dongxiao DAI and Yahong SHI},
title = {Clinical effect observation of Nd: YAG laser combined with acyclovir in the treatment of herpes labialis},
year = {2022},
journal = {Journal of Prevention and Treatment for Stomatological Diseases},
volume = {30},
number = {2},
pages = {123-126},
keywords = {herpes labialis, herpes simplex, Nd: YAG laser, low energy laser, acyclovir, clinical efficacy, the quality of life},
url = {https://www.sciopen.com/article/10.12016/j.issn.2096-1456.2022.02.008},
doi = {10.12016/j.issn.2096-1456.2022.02.008},
abstract = {ObjectiveTo investigate the clinical efficacy of Nd: YAG laser combined with 3% acyclovir cream in the treatment of herpes labialis.MethodsA total of 72 patients with herpes labialis were enrolled. According to the random number table method, the patients were divided into an observation group and a control group with 36 patients in the observation group and 36 patients in the control group. The Nd: YAG laser combined with 3% acyclovir cream was administered to the observation group, while 3% acyclovir cream was administered to the control group. The total effective rate, scab, scab removal, analgesic time, and quality of life were compared between the two groups.Results7 days after treatment, the total effective rate of clinical treatment in the control group was 27 patients (75%), and that in the observation group was 34 patients (94.4%); the contrast difference was statistically significant (P < 0.05). Compared with those in the control group, the crusting, prolapse and analgesic time of the observation group were shorter, and the differences were statistically significant (P < 0.05). Compared with the control group, the observation group had higher quality of life scores, and there was a statistical significance (P < 0.05).ConclusionFor patients with herpes labialis, using Nd: YAG laser combined with 3% acyclovir cream treatment can significantly improve the quality of life of patients and accelerate the speed of patient rehabilitation.}
}