@article{WANG2021, 
author = {Jue WANG and Qian WANG and Jia WU and Lingfeng LI and Xin SUI and Meihui LI and Xiao ZHANG and Ying GAO and Liuqing YANG and Zhihui LIU},
title = {Biomimetic restoration and regeneration of dentin and cementum},
year = {2021},
journal = {Journal of Prevention and Treatment for Stomatological Diseases},
volume = {29},
number = {6},
pages = {422-427},
keywords = {dentin, cementum, demineralization, remineralization, biomimetic restoration, regeneration, hydroxyapatite, collagen fibers, amorphous calcium phosphate, polymer-induced liquid precursor},
url = {https://www.sciopen.com/article/10.12016/j.issn.2096-1456.2021.06.011},
doi = {10.12016/j.issn.2096-1456.2021.06.011},
abstract = {Dental hard tissues lack the ability to self-heal. In dentin and cementum, hydroxyapatite (HA) can exist outside and/or inside collagen fibers. It is difficult to repair or regenerate HA with a highly ordered orientation in the presence of collagen fibers. At present, the biomimetic mineralization of dentin and cementum, mainly carried out by imitating its biological formation process and its physiological structure, can be divided into those originating from the fiber mineralization mechanism and those with HA as the main component. The materials used include natural materials such as demineralized dentin matrix (DDM) and calcined bovine hydroxyapatite (BHA), and synthetic materials such as polymer - induced liquid precursor (PILP) and synthetic HA. In the future, natural materials and synthetic materials should be combined for the restoration and regeneration of dentin and cementum by means of biomimetic mineralization of calcium phosphate released by remineralization solution-HA.}
}