@article{ZHU2020, 
author = {Shaojun ZHU and  RENA·Maimaiti and Bei ZHANG and Zhiheng WANG and Jinlian GE and Yishan LIU},
title = {Serum levels of iron, zinc, copper and vitamin D in severe early childhood caries},
year = {2020},
journal = {Journal of Prevention and Treatment for Stomatological Diseases},
volume = {28},
number = {8},
pages = {506-509},
keywords = {severe early childhood caries, deciduous tooth caries, trace elements, iron, zinc, copper, vitamin D, primary prevention},
url = {https://www.sciopen.com/article/10.12016/j.issn.2096-1456.2020.08.005},
doi = {10.12016/j.issn.2096-1456.2020.08.005},
abstract = {ObjectiveThe serum levels of iron, zinc, copper and vitamin D in severe early childhood caries (S-ECC) patients were investigated and analyzed to provide reference for primary prevention and diagnosis of S-ECC children.MethodsA total of 184 children were enrolled in the Children Health Department of Xinjiang Medical University Health Management Center from June 2018 to June 2019. They were divided into the caries-free (CF) group (n＝89) and S-ECC group (n＝95). The contents of iron, zinc, copper and vitamin D were detected.ResultsThe serum iron content of the CF group and S-ECC group was (8.36 ± 0.42) mmol/L and (8.13 ± 0.44) mmol/L, respectively, and the difference was statistically significant (t＝3.50, P < 0.001); the serum content of zinc was (83.18 ± 7.28) μmol/L and (79.23 ± 6.38) μmol/L, respectively, and the difference was statistically significant (t＝3.92, P < 0.001); the serum content of 25-hydroxyvitamin D was (86.72 ± 15.83) nmol/L and (77.75 ± 11.38) nmol/L, respectively, and the difference was statistically significant (t＝4.42, P < 0.001). The serum copper content of CF group and S-ECC group was (20.18 ± 4.84) μmol/L and (19.49 ± 4.62) μmol/L, but the difference was not statistically significant (t＝0.97, P＝0.33).ConclusionThe contents of iron, zinc and vitamin D in the serum of S-ECC patients are low, suggesting that iron, zinc and vitamin D supplementation should be emphasized in the prevention and treatment of S-ECC.}
}