@article{ZHAO2018, 
author = {Hua ZHAO and Xianing LI and Xianli ZENG and Hongyu ZHAO},
title = {Expression of periodontal ligament cell population miR-155 in patients with chronic periodontitis},
year = {2018},
journal = {Journal of Prevention and Treatment for Stomatological Diseases},
volume = {26},
number = {6},
pages = {370-373},
keywords = {Chronic periodontitis, Periodontal ligament cell population, Micro RNA, Micro-155, Regulate},
url = {https://www.sciopen.com/article/10.12016/j.issn.2096-1456.2018.06.006},
doi = {10.12016/j.issn.2096-1456.2018.06.006},
abstract = {ObjectiveTo understand the expression of miR-155 in the periodontal ligament cell population of patients with chronic periodontitis.MethodsPeriodontal ligament cells from the teeth of patients (n = 11) with chronic periodontitis were isolated and cultured, as were periodontal ligament cells from intact teeth obtained from healthy patients (n = 13) who had been treated with orthodontic extraction (the control group). The expression level of miR-155 in the two groups of periodontal ligament cell populations was detected by real-time fluorescence-based quantitative PCR.ResultsThe periodontal ligament cell expression level of miR-155 was significantly higher in the chronic periodontitis group (0.93 ± 0.12) than in the control group (0.76 ± 0.25) (P < 0.01).ConclusionmiR-155 expression in periodontal ligament cells was obviously stronger in patients with chronic periodontitis.}
}