TY  - JOUR
AU  - ZHAO, Hua
AU  - LI, Xianing
AU  - ZENG, Xianli
AU  - ZHAO, Hongyu
PY  - 2018
TI  - Expression of periodontal ligament cell population miR-155 in patients with chronic periodontitis
JO  - Journal of Prevention and Treatment for Stomatological Diseases
SN  - 2096-1456
SP  - 370
EP  - 373
VL  - 26
IS  - 6
AB  - ObjectiveTo understand the expression of miR-155 in the periodontal ligament cell population of patients with chronic periodontitis.MethodsPeriodontal ligament cells from the teeth of patients (n = 11) with chronic periodontitis were isolated and cultured, as were periodontal ligament cells from intact teeth obtained from healthy patients (n = 13) who had been treated with orthodontic extraction (the control group). The expression level of miR-155 in the two groups of periodontal ligament cell populations was detected by real-time fluorescence-based quantitative PCR.ResultsThe periodontal ligament cell expression level of miR-155 was significantly higher in the chronic periodontitis group (0.93 ± 0.12) than in the control group (0.76 ± 0.25) (P < 0.01).ConclusionmiR-155 expression in periodontal ligament cells was obviously stronger in patients with chronic periodontitis.
UR  - https://doi.org/10.12016/j.issn.2096-1456.2018.06.006
DO  - 10.12016/j.issn.2096-1456.2018.06.006