TY  - JOUR
AU  - ZHANG, Huan-dong
AU  - XIE, Si-ming
PY  - 2017
TI  - The research progress of Gli1 in the regulation of epithelial mesenchymal transition in oral squamous cell carcinoma
JO  - Journal of Prevention and Treatment for Stomatological Diseases
SN  - 2096-1456
SP  - 327
EP  - 330
VL  - 25
IS  - 5
AB  - HH (hedgehog) signal pathway consists the hedgehoge ligand (Shh、Ihh and Dhh), the Patch and Smo membrane protein complex and Zinc finger transcription factor Gli (Gli1, Gli2, Gli3). In HH (hedgehog) signaling pathway, Gli1 not only plays a dominant and decisive role in the zinc finger transcription factor Gli (Glioma-associated oncogene homolog) family, but also includes epithelial-mesenchymal transition (EMT) and oral squamous cell carcinoma, tumor invasion and metastasis. The research on oral squamous cell carcinoma and Shh/Gli1 signal axis is rare. In this paper, the squamous cell carcinoma of oral epithelial mesenchymal transformation and correlation study of quality Gli1 isreviewed.
UR  - https://doi.org/10.12016/j.issn.2096-1456.2017.05.011
DO  - 10.12016/j.issn.2096-1456.2017.05.011