TY  - JOUR
AU  - GUO, Yi
AU  - ZHOU, Lei
AU  - XIE, Jian-ya
PY  - 2016
TI  - The osteoplastic effect of Y500R coral hydroxyapatite composite grafts with fluoride on the rabbit skull
JO  - Journal of Prevention and Treatment for Stomatological Diseases
SN  - 2096-1456
SP  - 695
EP  - 700
VL  - 24
IS  - 12
AB  - ObjectiveTo explore the effect and changes in osteogenesis efficacy of CHA (Coral hydroxyapatite) composite grafts with fluoride in guided bone augmentation on rabbit skull.MethodsTwenty-four rabbits were studied. Y500R CHA composite grafts contained fluoride and titanium cylinders were prepared. Two titanium cylinders on the test group's rabbit skull were filled with composite grafts contain fluoride and non-fluoride grafts were filled in the control group. Cyclomycin and calcein were injected, After 2, 4 and 6 weeks, the animals were sacrificed to obtain ground sections for histology and histomorphometry. The general observation and area of highly fluorescent band of new bone formation was measured after sample treatment.ResultsSignificantly more neogenesis bone was augmented in the test groups than the control group. The osteoplastic effect in the test group more athletic. The experimental data had statistical significance (F = 6.36, P = 0.0193).ConclusionLow concentration (1.0 × 10-7 mol/L ~ 5.0 × 10-5 mol/L) fluoride can promote bone formation effectively.
UR  - https://doi.org/10.12016/j.issn.2096-1456.2016.12.003
DO  - 10.12016/j.issn.2096-1456.2016.12.003