@article{ZHENG2022, 
author = {Ziqing ZHENG and Bo NIU and Dingqiang LU and Guangchang PANG},
title = {Progress in Research on the Health Effects of Medium- and Long-Chain Free Fatty Acids and Their Receptors},
year = {2022},
journal = {Food Science},
volume = {43},
number = {19},
pages = {249-261},
keywords = {free fatty acid, free fatty acid receptor 1, free fatty acid receptor 4, taste, anti-inflammatory, agonist},
url = {https://www.sciopen.com/article/10.7506/spkx1002-6630-20210228-308},
doi = {10.7506/spkx1002-6630-20210228-308},
abstract = {Medium- and long-chain free fatty acids are not only an important source of energy for the body, but also important signal molecules in the body’s immunity. Recent studies have shown that medium- and long-chain free fatty acids interact with free fatty acid receptors (FFARs) 1 and 4 to regulate insulin secretion and inflammation and in turn the body’s immune system and metabolism. In this review, we discuss the nutritional role and metabolism of dietary medium- and longchain free fatty acids in the body, focusing on the latest progress in understanding the key physiological functions of medium and long-chain free fatty acids and their receptor-mediated signal pathways in taste signal transduction, metabolic regulation, and immune response and in research on synthetic agonists of FFAR1 and FFAR4.}
}