@article{Xue2025, 
author = {Yuanchao Xue and Filipe M. Cerqueira and Heather L. Stevenson and Natalie Williams-Bouyer and Rong Fang},
title = {Culture-negative liver abscess identified with plasma microbial cell-free DNA sequencing: A case report},
year = {2025},
journal = {Infectious Medicine},
volume = {4},
number = {2},
pages = {100180},
keywords = {Pyogenic liver abscess, Streptococcus anginosus group, Next-generation sequencing},
url = {https://www.sciopen.com/article/10.1016/j.imj.2025.100180},
doi = {10.1016/j.imj.2025.100180},
abstract = {Pyogenic liver abscess (PLA) is a potentially life-threatening disease. Early diagnosis and appropriate treatment are crucial to ensure high-quality healthcare for patients with PLA. However, this is complicated by their non-specific clinical symptoms. In addition, the etiologic organisms responsible for PLA are frequently culture-negative, thus complicating clinical decision-making. Here, we report a case of PLA caused by Streptococcus intermedius, as identified via DNA metagenomic sequencing of plasma.}
}