@article{Yen2025, 
author = {Chi-Hua Yen and Yohanes Tandoro and Yu-Hsuan Liu and Bo-Kai Chen and Asif Ali and You-Cheng Shen and Chin-Kun Wang},
title = {The effect of L-carnitine and catechin together with calories restriction on the reduction of body fat and blood lipids},
year = {2025},
journal = {Journal of Food Bioactives},
volume = {30},
pages = {47-56},
keywords = {Catechin, Body fat, 3T3-L1 adipocytes, Lipid profiles, L-Carnitine},
url = {https://www.sciopen.com/article/10.26599/JFB.2025.95030414},
doi = {10.26599/JFB.2025.95030414},
abstract = {Obesity has become a critical health problem worldwide, and it’s associated with other health issues. Weight loss supplement and caloriese restriction from the daily diet can be implemented to help reduce body weight. L-carnitine and catechin can help reduce body weight by upregulating fatty acid metabolism and altering lipid formation. This study was to assess the effect of L-carnitine and catechin together with calories restriction on body weight and lipid profile. 3T3-L1 cell line was used to assess the effect of L-carnitine and catechin on lipid accumulation. For the human study, a total 30 subjects with obesity were recruited and divided into 2 intervention groups, one is calories restriction group and the other one is L-carnitine and catechin together with calories restriction. Result shows that L-carnitine and catechin significantly reduced fat accumulation in the 3T3-L1 cell model. In the human study, L-carnitine and catechin together with calories restriction significantly reduced body weight, and body fat and improved the lipid profile of the subject, and showed better effect than calories restriction only.}
}