@article{Bin2025, 
author = {Fan-Chun Bin and Xin-Yi Wu and Jie Liu and Xian-Zi Dong and Teng Li and Qi Duan and Jian-Miao Zhang and Katsumasa Fujita and Mei-Ling Zheng},
title = {Micropattern of core-shell Ag@MCS/PEGDA nanoparticles fabricated by femtosecond laser maskless optical projection lithography},
year = {2025},
journal = {International Journal of Extreme Manufacturing},
volume = {7},
number = {3},
keywords = {femtosecond laser maskless optical projection lithography, micropatterns, Ag@MCS/PEGDA nanoparticles, core-shell nanomaterials},
url = {https://www.sciopen.com/article/10.1088/2631-7990/ada83a},
doi = {10.1088/2631-7990/ada83a},
abstract = {Chitosan (CS)-based nanocomposites have been studied in various fields, requiring a more facile and efficient technique to fabricate nanoparticles with customized structures. In this study, Ag@methacrylamide CS/poly(ethylene glycol) diacrylate (Ag@MP) micropatterns are successfully fabricated by femtosecond laser maskless optical projection lithography (Fs-MOPL) for the first time. The formation mechanism of core-shell nanomaterial is demonstrated by the local surface plasmon resonances and the nucleation and growth theory. Amino and hydroxyl groups greatly affect the number of Ag@MP nanocomposites, which is further verified by replacing MCS with methacrylated bovine serum albumin and hyaluronic acid methacryloyl, respectively. Besides, the performance of the surface-enhanced Raman scattering, cytotoxicity, cell proliferation, and antibacterial was investigated on Ag@MP micropatterns. Therefore, the proposed protocol to prepare hydrogel core-shell micropattern by the home-built Fs-MOPL technique is prospective for potential applications in the biomedical and biotechnological fields, such as biosensors, cell imaging, and antimicrobial.}
}