@article{Liu2025, 
author = {Xinqi Liu and Aoxiang Huang and Wei Ni and Yi Fang and Fuxiang Wei and Shan Huang and Qi Xiao},
title = {Efficient and accessible detection of organophosphorus pesticides in food using Pr6O11/Zr-MOF nanozyme: Advancing food safety},
year = {2025},
journal = {Nano Research},
volume = {18},
number = {8},
pages = {94907620},
keywords = {nanozyme, food safety, organophosphorus pesticides, universal detection, Pr6O11/Zr-metal–organic framework (MOF)},
url = {https://www.sciopen.com/article/10.26599/NR.2025.94907620},
doi = {10.26599/NR.2025.94907620},
abstract = {The universality of detecting organophosphorus pesticides in vegetables and fruits is crucial for ensuring food safety; however, this remains a challenge. In this study, we successfully developed an efficient nanozyme for organophosphorus detection with easy-to-interpret visual results, using Zr-metal–organic framework (MOF) to anchor Pr6O11. The detection capability of Pr6O11, which arises from the polyvalent states of metal atomic orbitals, was significantly enhanced by Zr-MOF. This combination prevented Pr6O11 aggregation and enriched organophosphorus compounds in the environment through coordination, allowing the colorimetric method to achieve a limit of detection (LOD, signal-to-noise ratio (S/N) = 3) as low as 1.47 μg·mL−1. Additionally, the method provides a visual and rapid result interpretation via red–green–blue (RGB) color analysis using a smartphone app, making it accessible for non-experts. To demonstrate its accessibility, organophosphorus residues in commercially available cucumbers, lettuce, and rapeseed were investigated, validating the method with a spiked recovery test. The recovery rates ranged from 95% to 105%, with a relative error of less than 5%. The reaction time of the method was as short as 40 min, confirming its reliability and accessibility. Therefore, the Pr6O11/Zr-MOF nanozyme, coupled with the smartphone app, offers a reliable organophosphorus detection method with significant implications for food safety.}
}