@article{LIU2025, 
author = {Xiaojia LIU and Xiaomei ZHANG and Minghui ZHANG and Xing LI and Ziyue GAO and Junying ZHAO and Weicang QIAO and Lijun CHEN},
title = {Research Progress in Types, Functions and Detection Techniques of Glycoproteins in Breast Milk},
year = {2025},
journal = {Food Science},
volume = {46},
number = {6},
pages = {371-380},
keywords = {proteomics, glycoprotein, glycosylation site, biological function, detection techniques, breast milk},
url = {https://www.sciopen.com/article/10.7506/spkx1002-6630-20240910-084},
doi = {10.7506/spkx1002-6630-20240910-084},
abstract = {More than 70% of proteins in breast milk are glycosylated, and glycosylation enzymes cleave specific structures that connect proteins to polysaccharides. However, the human digestive system does not secrete glycosylation enzymes. Therefore, glycosylated proteins are more likely to retain their activity and exert their functions in the digestive system compared with non-glycosylated proteins. This article introduces the types, composition and content of glycoproteins in breast milk, analyzes the mechanism underlying their biological functions, and reviews recent progress in glycoproteomics. We expect that this review will provide a reference for research on the biological functions of glycoproteins in breast milk.}
}