@article{ZHOU2025, 
author = {Yongtai ZHOU and Zhenyu YANG and Yan LI and Jiajing WU and Bo ZHAO},
title = {Research Progress on the Mechanism of Lipocalin-2 in Neurological Diseases},
year = {2025},
journal = {Medical Journal of Peking Union Medical College Hospital},
volume = {16},
number = {2},
pages = {330-337},
keywords = {lipocalin-2, cerebrovascular disease, cognitive impairment diseases, neurodegenerative disease, anxiety disorders, depression},
url = {https://www.sciopen.com/article/10.12290/xhyxzz.2025-0028},
doi = {10.12290/xhyxzz.2025-0028},
abstract = {Lipocalin-2 (LCN2), a member of the human lipocalin family, has been demonstrated to be closely associated with diabetes, cardiovascular diseases, and renal disorders. Recent studies have indicated that LCN2 plays a significant regulatory role in the pathogenesis and progression of various neurological diseases by mediating pathways such as inflammation, oxidative stress, and ferroptosis. This article reviews the research advancements on the mechanism of LCN2 in neurological disorders, including cerebrovascular diseases, cognitive impairment disorders, Parkinson's disease, depression, and anxiety disorders, aiming to enhance clinical understanding.}
}