@article{Zhang2025, 
author = {Tianyao Zhang and Haibo Yu and Guoqiang Gu and Jienan Shen and Huitao Zhang and Zitong Yu and Shi Hu and Hui Yang},
title = {Real-time observation and synchronous nanomanipulation platform based on microlens and atomic force microscopy coupling},
year = {2025},
journal = {Nano Research},
volume = {18},
number = {6},
pages = {94907397},
keywords = {microlens, atomic force microscopy (AFM), optical super-resolution imaging, nanomanipulation, microsphere},
url = {https://www.sciopen.com/article/10.26599/NR.2025.94907397},
doi = {10.26599/NR.2025.94907397},
abstract = {Nanomanipulation based on atomic force microscopy (AFM) is widely used in various fields, including nanoparticle assembly, nanostructure construction, and semiconductor device manufacturing. However, a challenge remains in the lack of nanoscale visual feedback, which limits operational efficiency and accuracy. Here, we present a method for nanomanipulation under the visual guidance of real-time super-resolution imaging. The method involves coupling a microlens to the end of a conventional AFM probe cantilever and depositing a diamond tip onto the surface of the microlens using focused ion beam (FIB). The resulting microlens-AFM probe enhances the imaging resolution of traditional AFM optical systems, providing super-resolution capability with a multiple 3× increase in optical imaging magnification and enabling synchronous imaging and manipulation of silver nanowires with a characteristic size of 200 nm. This advancement bridges the key gap in AFM-based nanomanipulation by providing in-situ, real-time, non-destructive, and ultra-high-resolution visual feedback. This technology has the potential to provide new methods and key technologies for research in a wide range of applications, including nanorobots, nanoobservation, nanomanipulation, and manufacturing.}
}