@article{Akbarzadeh2024, 
author = {Fatemeh Zahra Akbarzadeh and Masoud Sarraf and Erfan Rezvani Ghomi and Vishnu Vijay Kumar and Mojtaba Salehi and Seeram Ramakrishna and Sungchul Bae},
title = {A state-of-the-art review on recent advances in the fabrication and characteristics of magnesium-based alloys in biomedical applications},
year = {2024},
journal = {Journal of Magnesium and Alloys},
volume = {12},
number = {7},
pages = {2569-2594},
keywords = {Mg-based alloys, Biocompatibility, Anti-microbial strategies, Additive manufacturing, Mg implants},
url = {https://www.sciopen.com/article/10.1016/j.jma.2024.06.015},
doi = {10.1016/j.jma.2024.06.015},
abstract = {Magnesium (Mg) and its alloys have recently gained increasing attention in the biomedical field as promising biodegradable materials with harmless degradation products. Magnesium-based alloys have a wide range of biomedical applications because of their outstanding biocompatibility and unique mechanical properties. Widespread use of Mg-based biomedical devices eliminates the need for post-healing biomaterial removal surgery and minimizes the negative consequences of the implantation of permanent biomaterials, including stress shielding and undesired metal ion release in the body. This paper provides a literature review on the properties and manufacturing methods of Mg-based alloys for biomedical applications, including orthopedic implants, cardiovascular applications, surgical wires and staplers, and antitumor activities. Each application of Mg-based biomaterials is investigated from a biological perspective, including matching functional properties, biocompatibility, host tissue responses, and anti-microbial strategies, along with potential additive manufacturing technologies for these applications. Finally, an outlook is presented to provide recommendations for Mg-based biomaterials in the future.}
}