@article{Wu2025, 
author = {Wenxiu Wu and Wenzheng Liu and Yingying Jing and Zhao Wang and Yurong Guo and Jiayao Ni and Xing Gao and Wensi Li and Jibin Song},
title = {Research status and prospects of covalent organic frameworks in the antibacterial field},
year = {2025},
journal = {Nano Research},
volume = {18},
number = {2},
pages = {94907161},
keywords = {covalent organic frameworks, antibacterial potential, framework chemistry, pore chemistry, composite material, nanozymes},
url = {https://www.sciopen.com/article/10.26599/NR.2025.94907161},
doi = {10.26599/NR.2025.94907161},
abstract = {Covalent organic frameworks (COFs), as an emerging class of crystalline porous polymeric material, process large surface area, ordered pore structure, good biocompatibility, excellent chemical stability, and low toxicity, making it an excellent candidate for nanotherapeutics. In this article, the recent research progress of COFs was reviewed in the antibacterial field. We introduced the antibacterial potential of COF materials themselves, covering framework structures and pore chemistry. Moreover, the synergistic antibacterial effects of COF composites were discussed, which were formed by the combination of COF with other nanomaterials. In addition, the excellent performances of COFs as nanozymes were investigated in antibacterial applications. Currently, COF-based high-efficiency antibacterial agents face great challenges and prospects in practical applications. The review will provide new COF-based methods for resolving drug-resistant bacterial issues.}
}