@article{Gao2024, 
author = {Peng Gao and Feifan Chen and Haitang Liu and Shijun Fan and Jierui Zeng and Xue Diao and Yang Liu and Wencheng Song and Shifu Wang and Jing Li and Xiaobo Zhu and Bin Tu and Weilan Chen and Ting Li and Yuping Wang and Bingtian Ma and Shigui Li and Hua Yuan and Peng Qin},
title = {qGW11a/OsCAT8, encoding an amino acid permease, negatively regulates grain size and weight in rice},
year = {2024},
journal = {The Crop Journal},
volume = {12},
number = {4},
pages = {1150-1158},
keywords = {Rice, Grain size, Grain weight, QTL, OsCAT8},
url = {https://www.sciopen.com/article/10.1016/j.cj.2024.07.001},
doi = {10.1016/j.cj.2024.07.001},
abstract = {Grain size is a key factor influencing grain weight in rice. In this study, a chromosome segment substitution line (CSSL9-17) was identified, that exhibits a significant reduction in both grain size and weight compared to its donor parent 93-11. Further investigation identified two quantitative trait loci (QTL) on chromosome 11, designated qGW11a and qGW11b, which contribute to 1000-grain weight with an additive effect. LOC_Os11g05690, encoding the amino acid permease OsCAT8, is the target gene of qGW11a. Overexpression of OsCAT8 resulted in decreased grain weight, while OsCAT8 knockout mutants exhibited increased grain weight. The 287-bp located within the OsCAT8 promoter region of 93-11 negatively regulates its activity, which is subsequently correlated with an increase in grain size and weight. These results suggest that OsCAT8 functions as a negative regulator of grain size and grain weight in rice.}
}