TY - JOUR AU - Finsterer, Josef AU - Scorza, Fulvio A. AU - de Almeida, Antonio-Carlos G. PY - 2023 TI - Establishing causality between SARS-CoV-2 and stroke/bleeding requires a temporal relationship and plausible pathophysiology JO - Brain Hemorrhages SN - 2589-238X SP - 174 EP - 175 VL - 4 IS - 3 AB - Cerebrovascular events are increasingly recognized as a complication of SARS-CoV-2 infections. They can be due to hypercoagulability, vasculopathy, cardiac involvement in the infection, or autonomic dysfunction. However, establishing a causal relationship between cerebrovascular events and viral infection is not always easy and requires thorough investigation and documentation of a close temporal relationship between SARS-CoV-2 infection and the onset of cerebral impairment. Establishing a causal relationship between SARS-CoV-2 infection and cerebrovascular events is desirable as it can guide therapeutic management and determine the outcome. UR - https://doi.org/10.1016/j.hest.2022.10.004 DO - 10.1016/j.hest.2022.10.004