@article{Li2023, 
author = {Yiming Li and Jing Xiao and Fang Xie and Yu Lin and Mingbo Zhang and Yukun Luo},
title = {The Value of CEUS in the Diagnosis and Treatment of Thyroid Primary Squamous Cell Carcinoma: A Case Report},
year = {2023},
journal = {Advanced Ultrasound in Diagnosis and Therapy},
volume = {7},
number = {4},
pages = {412-415},
keywords = {Ultrasonography, Image enhancement, Thyroid gland, Squamous cell carcinoma, Biopsy},
url = {https://www.sciopen.com/article/10.37015/AUDT.2023.220027},
doi = {10.37015/AUDT.2023.220027},
abstract = {Primary squamous cell carcinoma of the thyroid (PSCCT) is a rare clinical disease characterized by rapid growth, high invasiveness, and a poor prognosis. A 66-year-old male patient was admitted due to throat pain and dysphagia. Ultrasound revealed a calcified hypoechoic mass in the right lobe of the thyroid gland, measuring approximately 35.3 ml. Ultrasound and PET-CT both indicated high suspicion of malignancy. The patient underwent contrast-enhanced US-guided biopsy, and the pathological results revealed poorly differentiated squamous cell carcinoma. CEUS was performed regularly during the Chemotherapy combined with pembrolizumab (PD-1) treatment courses. The vital area was significantly reduced with neither recurrence nor cervical lymph node metastasis. Surgical resection and chemotherapy combined with immunotherapy had a significant treatment effect in this case. CEUS is helpful for diagnosis confirmation, biopsy guidance and efficacy evaluation and has important clinical application value.}
}