@article{Wei2024, 
author = {Ziyu Wei and Wenting Li and Zhifang Liu and Yongfa Zhu and Huaqiang Cao},
title = {Hydrogen bond-bridged phosphorene flexible film for photodynamic inhibiting Staphylococcus aureus},
year = {2024},
journal = {Nano Research},
volume = {17},
number = {6},
pages = {5461-5468},
keywords = {Staphylococcus aureus, phosphorene, hydrogen bond-bridged, flexible film, photodynamic},
url = {https://www.sciopen.com/article/10.1007/s12274-024-6487-7},
doi = {10.1007/s12274-024-6487-7},
abstract = {Antibiotics are a widely used and effective treatment for bacterial infections. However, bacteria can gradually evolve during infection, leading to developing resistance to antibiotics, which renders previously effective treatments ineffective. Finding a useful and convenient manner to treat bacterial infections is a great challenge. Here, we report a flexible hydrogen-bond-bridged phosphorene film with photodynamic antibacterial properties and excellent mechanical properties, fabricated from electrochemical exfoliation of black phosphorus (BP). When illuminated under 700 nm light, the hydrogen bond-bridged phosphorene flexible film is capable of converting ground-state triplet oxygen (O2) into excited-state singlet oxygen (1O2), destroying the structure of the membrane of Staphylococcus aureus, and eventually leading to bacterial death, via breaking the C=C of unsaturated fatty acids within the bacterial cell membrane after the reaction between 1O2 and unsaturated fatty acids, thus realizing a highly efficient antibacterial approach, which is supported by gas chromatography-mass spectrometry (GC-MS) technique. This work establishes an effective phototherapy platform for treating bacterial traumatic infections.}
}