@article{Oh2019, 
author = {Won Young Oh and Yi-Shiou Chiou and Pei-Sheng Lee and Min-Hsiung Pan and Fereidoon Shahidi},
title = {Lipophilized resveratrol affects the generation of reactive nitrogen species in murine macrophages and cell viability of human cancer cell lines},
year = {2019},
journal = {Journal of Food Bioactives},
volume = {7},
pages = {73-77},
keywords = {Resveratrol ester, Antioxidant activity, Anti-inflammatory activity, Anti-proliferative effect},
url = {https://www.sciopen.com/article/10.31665/JFB.2019.7201},
doi = {10.31665/JFB.2019.7201},
abstract = {Resveratrol was esterified with selected fatty acids to improve its lipophilicity and potential application in food and biological systems. In this study, resveratrol and monoesters of resveratryl propionate (RC3:0) and resveratryl docosahexaenate (RDHA) were examined for their effects on anti-inflammatory and anti-proliferative activity in vitro. All test compounds showed a decreased nitrite production in murine RAW 264.7 cells in a concentration dependent manner. Resveratrol, RC3:0, and RDHA were evaluated for their effects on cell viability using liver cancer (HepG2), colon cancer (HT-29, A431), breast cancer (MCF7), and gastric cancer (AGS) cell lines. All test compounds showed decreased cell viability of HepG2, A431, MCF7, HT-29, and AGS in a concentration-dependent manner. The results suggest that resveratrol esters may serve as potential anti-inflammatory and anti-proliferative agents.}
}