@article{Wang2024, 
author = {Shiyao Wang and Yanan Zhao and Xiao Wei and Yisheng Chen},
title = {Facile SERS screening of melamine in bovine milk with 2D printed AgNPs/glass fabric filter paper as the flexible substrate},
year = {2024},
journal = {Food Science and Human Wellness},
volume = {13},
number = {5},
pages = {2595-2600},
keywords = {2D print, Melamine, Milk, Surface-enhanced Raman spectroscopy (SERS), flexible substrate},
url = {https://www.sciopen.com/article/10.26599/FSHW.2022.9250208},
doi = {10.26599/FSHW.2022.9250208},
abstract = {Melamine is one of the most frequently detected adulterants in dairy products. The current study proposes a surface-enhanced Raman spectroscopy (SERS)-based analytical tool for fast and reliable screening of melamine in bovine milk. A hand-held Raman spectrometer was used in conjunction with a substrate composed of silver nanoparticles (AgNPs) that was 2D printed onto glass fiber (GF) filter paper. Under optimized conditions, a sensitive and fingerprint-like signal at 674 cm−1 was obtained. The AgNPs/GF substrate exhibited high sensitivity to melamine in milk down to 1.9498×10−5 mg/mL, which is well below the USA and EU safety limits (2.5×10−3 mg/mL). Remarkably, the proposed technology was also highly reproducible, showing spot-to-spot and block-to-block variations below 3.3% and 4.9% at 674 cm−1 in Raman intensity, respectively. The characteristic peak intensity and concentration of melamine showed an acceptable linear relationship (R2=0.9909) within the range of 0.0001-1 mg/mL. Overall, the method established in this study can provide an efficient and effective method for the quantitative target screening and detection of melamine in dairy products.}
}