@article{Khalaf2023, 
author = {Majid S. Khalaf and Marwa Abdul Muhsien Hassan and Asmaa Hadi Mohammed},
title = {Exploring the Role of Phytochemicals: Effect of [6]-Gingerol Combined with Colloidal Gold Nanoparticles on Thyroid Carcinoma Cells},
year = {2023},
journal = {Nano Biomedicine and Engineering},
volume = {15},
number = {1},
pages = {36-41},
keywords = {colloidal gold, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) cytotoxicity, [6]-gingerol, 2,2-diphenyl-1-picrylhydrazyl (DPPH)},
url = {https://www.sciopen.com/article/10.26599/NBE.2023.9290015},
doi = {10.26599/NBE.2023.9290015},
abstract = {Gold nanostructure can be manufactured in many forms, such as spherical by using simple chemical method.  X-ray powder diffraction (XRD) pattern of gold nanoparticles (AuNPs) was derived from a 400-μL trisodium citrate solution. The diffraction peaks corresponding to the diffraction planes of (111), (200), and (220) were all indexed to the gold with a face-centered cubic structure. The lattice constant calculated from the XRD pattern is 4.078 Å, which matches the conventional cubic gold metal diffraction pattern well (Pattern card number (04-784)). The results of scanning electronic microscope show that the biological nanoparticles of gold have asymmetric shapes and different sizes grouped as a circular particle. It was observed that the fashioning of AuNPs increased with increase in the concentration of [6]-gingerol waste extracts. The viability of FTC-133 cells treated for 48 h with various concentrations of [6]-gingerol extract coated with AuNPs (12.5–400 g/mL) was used to determine the cytotoxicity. A dose-dependent reduction in FTC-133 cell viability caused by [6]-gingerol extract capped with Au NPs was substantial (P < 0.05), reaching 75% cell mortality at 400 g/mL; the IC50 was 90.5%.}
}