TY - JOUR AU - Chen, Wenzhao AU - Liu, Li AU - Hang, Jian AU - Li, Yuguo PY - 2023 TI - Predominance of inhalation route in short-range transmission of respiratory viruses: Investigation based on computational fluid dynamics JO - Building Simulation SN - 1996-3599 SP - 765 EP - 780 VL - 16 IS - 5 AB - During the coronavirus disease 2019 pandemic, short-range virus transmission has been observed to have a higher risk of causing infection than long-range virus transmission. However, the roles played by the inhalation and large droplet routes cannot be distinguished in practice. A recent analytical study revealed the predominance of short-range inhalation over the large droplet spray route as causes of respiratory infections. In the current study, short-range exposure was analyzed via computational fluid dynamics (CFD) simulations using a discrete phase model. Detailed facial membranes, including eyes, nostrils, and a mouth, were considered. In CFD simulations, there is no need for a spherical approximation of the human head for estimating deposition nor the "anisokinetic aerosol sampling" approximation for estimating inhalation in the analytical model. We considered two scenarios (with two spheres [Scenario 1] and two human manikins [Scenario 2]), source–target distances of 0.2 to 2 m, and droplet diameters of 3 to 1,500 μm. The overall CFD exposure results agree well with data previously obtained from a simple analytical model. The CFD results confirm the predominance of the short-range inhalation route beyond 0.2 m for expiratory droplets smaller than 50 μm during talking and coughing. A critical droplet size of 87.5 μm was found to differentiate droplet behaviors. The number of droplets deposited on the target head exceeded those exposed to facial membranes, which implies a risk of exposure through the immediate surface route over a short range. UR - https://doi.org/10.1007/s12273-022-0968-y DO - 10.1007/s12273-022-0968-y