TY - JOUR AU - Ismail, Ahmad Hussein AU - Al-Bairmani, Hassanain Kamil AU - Abbas, Zainab Sabri AU - Rheima, Ahmed Mahdi PY - 2020 TI - Synthesis, Characterization, Spectroscopic and Biological Studies of Zn(Ⅱ), Mn(Ⅱ) and Fe(Ⅱ) Theophylline Complexes in Nanoscale JO - Nano Biomedicine and Engineering SN - 2097-3837 SP - 253 EP - 261 VL - 12 IS - 3 AB - Three nanocomplexes of Zn(Ⅱ), Mn(Ⅱ), Fe(Ⅱ) with theophylline were synthesized by ultrasonic sonication method. Melting point, molar conductivity, solubility, flame atomic absorption, Fourier-transform infrared spectroscopy (FTIR), ultraviolet-visible (UV-vis) spectroscopy and C/H/N elemental analyses were used to investigate and suggest the structure of the nanocomplexes. Size and morphology of the nanocomplexes were measurement by transmission electron microscopy (TEM), ranging from 6-22 nm. Efficacy of the nanocomplexes synthesized was examined against four types of bacterial strains: Staphylococcus aureus, Bacillus subtilis (Gram-positive bacteria), Klebsiella pneumonia and Escherichia coli (Gram-negative bacteria). The results showed that all nanocomplexes had very high susceptibility to inhibit bacterial growth, as indicated by their inhibition zones between 98% and 100%. UR - https://doi.org/10.5101/nbe.v12i3.p253-261 DO - 10.5101/nbe.v12i3.p253-261