@article{Song2023, 
author = {Bo Song and Lei Jiang},
title = {A four-dimensional model for the information storage/output of life},
year = {2023},
journal = {Nano Research},
volume = {16},
number = {2},
pages = {2630-2634},
keywords = {cell, nervous system, four-dimensional (4D) storage/output model, life information},
url = {https://www.sciopen.com/article/10.1007/s12274-022-4885-4},
doi = {10.1007/s12274-022-4885-4},
abstract = {A large amount of progress has achieved in neuroscience, however, there is still a lack of reasonable model for the storage/output (S/O) of life information. The cyclical motion of cardio- and pulmonary-myocyte is a typical process of the life information S/O, while the opening and closing sites of Ca2+ ion channels during the motion can form a genetically programmed time-dependent three-dimensional (3D) pattern. Those phenomena indicate a strong correlation of the information S/O model of these myocytes with the time-sequence 3D patterns. Therefore, based on the time-dependent Ca2+ fluorescence imaging during the motion of cardio- and pulmonary-myocyte, here we suggest a four-dimensional (4D) code of information S/O model in cell and nervous system. Further from the fact of pulmonary myocyte motion able to be controlled by brain, it is deduced that the 4D code in brain has a role of controlling muscles through a pathway of the central nervous system, peripheral nervous system, neuromuscular junction, and muscle cells. In addition, we also suggested the 4D code of non-innate skill that can be programmed by the learning/training of a long time (~ 3 years), such as walking, writing, painting, sports, speech, singing, and dancing. Noticeably, this 4D S/O model is reasonable for the ultralow energy consumption of life information transmission.}
}