@article{Chen2016, 
author = {Tuoyu Chen and Yuqi Zhang and Huancong Zuo and Yapeng Zhao and Chaoqiang Xue and Bin Luo and Qinglin Zhang and Jin Zhu and Xiumei Wang and Fuzhai Cui},
title = {Repairing skull defects in children with nano-hap/collagen composites: A clinical report of thirteen cases},
year = {2016},
journal = {Brain Science Advances},
volume = {2},
number = {1},
pages = {31-37},
keywords = {cranioplasty, children, biomimetic bone, 3D printing},
url = {https://www.sciopen.com/article/10.18679/CN11-6030_R.2016.005},
doi = {10.18679/CN11-6030_R.2016.005},
abstract = {Objective:To evaluate the clinical results of repairing skull defects with biomimetic bone (nano-hap/collagen composites, NHACs) in children.Methods:Thirteen children with skull defects were treated with NHACs in our hospital. The NHACs molded with the help of a 3D printer were used in the operations.Results:All 13 operations were successful, and patients recovered without infection. Only one patient suffered from subcutaneous hydrops post-operation. The implanted NHACs remained fixed well after 1 year, and their CT HU values raised gradually. Skull shapes of children developed normally. Recovery of neurological and cognitive function was significant.Conclusions:NHAC, chosen to repair skull defects in children, can coexist with normal skull and reduce the negative effects on growth and development. NHAC could be a good choice for children with skull defects.}
}