@article{Zhou2021, 
author = {Lu Zhou and Liping Chen and Zhenyao Ding and Dandan Wang and Hao Xie and Weihai Ni and Weixiang Ye and Xiqi Zhang and Lei Jiang and Xinjian Feng},
title = {Enhancement of interfacial catalysis in a triphase reactor using oxygen nanocarriers},
year = {2021},
journal = {Nano Research},
volume = {14},
number = {1},
pages = {172-176},
keywords = {biocatalysis, oxidase kinetics, triphase interface, oil core-silica shell sphere},
url = {https://www.sciopen.com/article/10.1007/s12274-020-3062-8},
doi = {10.1007/s12274-020-3062-8},
abstract = {Multiphase catalysis is used in many industrial processes; however, the reaction rate can be restricted by the low accessibility of gaseous reactants to the catalysts in water, especially for oxygen-dependent biocatalytic reactions. Despite the fact that solubility and diffusion rates of oxygen in many liquids (such as perfluorocarbon) are much higher than in water, multiphase reactions with a second liquid phase are still difficult to conduct, because the interaction efficiency between immiscible phases is extremely low. Herein, we report an efficient triphase biocatalytic system using oil core-silica shell oxygen nanocarriers. Such design offers the biocatalytic system an extremely large water-solid-oil triphase interfacial area and a short path required for oxygen diffusion. Moreover, the silica shell stabilizes the oil nanodroplets in water and prevents their aggregation. Using oxygen-dependent oxidase enzymatic reaction as an example, we demonstrate this efficient biocatalytic system for the oxidation of glucose, choline, lactate, and sucrose by substituting their corresponding oxidase counterparts. A rate enhancement by a factor of 10-30 is observed when the oxygen nanocarriers are introduced into reaction system. This strategy offers the opportunity to enhance the efficiency of other gaseous reactants involved in multiphase catalytic reactions.}
}