@article{Yan2008, 
author = {Juan Yan and Mei Hu and Di Li and Yao He and Rui Zhao and Xingyu Jiang and Shiping Song and Lianhui Wang and Chunhai Fan},
title = {A Nano- and Micro-Integrated Protein Chip Based on Quantum Dot Probes and a Microfluidic Network},
year = {2008},
journal = {Nano Research},
volume = {1},
number = {6},
pages = {490-496},
keywords = {Quantum dots, microfluidics, carcinoma embryonic antigen (CEA), microarray, polydimethylsiloxane (PDMS)},
url = {https://www.sciopen.com/article/10.1007/s12274-008-8052-1},
doi = {10.1007/s12274-008-8052-1},
abstract = {A novel nano- and micro-integrated protein chip (NMIPC) that can detect proteins with ultrahigh sensitivity has been fabricated. A microfluidic network (μFN) was used to construct the protein chips, which allowed facile patterning of proteins and subsequent biomolecular recognition. Aqueous phase-synthesized, water-soluble fluorescent CdTe/CdS core-shell quantum dots (aqQDs), having high quantum yield and high photostability, were used as the signaling probe. Importantly, it was found that aqQDs were compatible with microfluidic format assays, which afforded highly sensitive protein chips for cancer biomarker assays.}
}