@article{Meng2020, 
author = {Yanxia Meng and Kunfeng Zhao and Zhaokun Zhang and Peng Gao and Jing Yuan and Ting Cai and Qin Tong and Gang Huang and Dannong He},
title = {Effects of crystal structure on the activity of MnO2 nanorods oxidase mimics},
year = {2020},
journal = {Nano Research},
volume = {13},
number = {3},
pages = {709-718},
keywords = {MnO2, glutathione, crystal phase structure, oxidase mimics, surface hydroxyls, 3, 3', 5, 5'-tetramethylbenzidine (TMB)},
url = {https://www.sciopen.com/article/10.1007/s12274-020-2680-5},
doi = {10.1007/s12274-020-2680-5},
abstract = {The crystal structures would directly affect the physical and chemical properties of the surface of the material, and would thus influence the catalytic activity of the material. α-MnO2, β-MnO2 and γ-MnO2 nanorods with the same morphology yet different crystal structures were prepared and tested as oxidase mimics using 3,3',5,5'-tetramethylbenzidine (TMB) as the substrate. β-MnO2 that exhibited the highest activity had a catalytic constant of 83.75 μmol·m-2·s-1, 2.7 and 19.0 times of those of α-MnO2 and γ-MnO2 (30.91 and 4.41 μmol·m-2·s-1), respectively. The characterization results showed that there were more surface hydroxyls as well as more Mn4+ on the surface of the β-MnO2 nanorods. The surface hydroxyls were conducive to the oxidation reaction, while Mn4+ was conducive to the regeneration of surface hydroxyls. The synergistic effect of the two factors significantly improved the activity of β-MnO2 oxidase mimic. Using β-MnO2, a β-MnO2-TMB-GSH system was established to detect the content of glutathione (GSH) rapidly and sensitively by colorimetry. This method had a wide detection range (0.11-45 μM) and a low detection limit (0.1 μM), and had been successfully applied to GSH quantification in human serum samples.}
}