@article{Cui2015, 
author = {Rongli Cui and Juan Li and Huan Huang and Mingyi Zhang and Xihong Guo and Yanan Chang and Min Li and Jinquan Dong and Baoyun Sun and Gengmei Xing},
title = {Novel carbon nanohybrids as highly efficient magnetic resonance imaging contrast agents},
year = {2015},
journal = {Nano Research},
volume = {8},
number = {4},
pages = {1259-1268},
keywords = {graphene oxide, metallofullerene, magnetic resonance imaging (MRI), nanohybrids},
url = {https://www.sciopen.com/article/10.1007/s12274-014-0613-x},
doi = {10.1007/s12274-014-0613-x},
abstract = {Novel carbon nanohybrids based on unmodified metallofullerenes have been successfully fabricated for use as a new magnetic resonance imaging (MRI) contrast agent. The nanohybrids showed higher R1 relaxivity and better brightening effect than Gd@C82(OH)X, in T1-weighted MR images in vivo. This is a result of the proton relaxivity from the original gadofullerenes, which retained a perfect carbon cage structure and so might completely avoid the release of Gd3+ ions. A "secondary spin-electron transfer" relaxation mechanism was proposed to explain how the encaged Gd3+ ions of carbon nanohybrids interact with the surrounding water molecules. This approach opens new opportunities for developing highly efficient and low toxicity MRI contrast agents.}
}